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Sudden onset acute liver failure in a patient with clinically occult small cell lung carcinoma: autopsy report and review of the medical literature

Massimiliano Guerriero; Arnaldo Carbone; Francesco Colasurdo; Valerio Pellegrini; Anna Maria Pollio

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Liver metastases are commonly found in advanced cancer patients; however, acute liver failure secondary to diffuse liver infiltration is rare. Small cell lung carcinoma accounts for 15% of lung carcinomas. We describe the ninth case of small cell lung carcinoma massively metastatic to the liver, reported in the scientific literature, with sudden clinical onset and death after a few days. An autopsy was performed to understand the cause of death.


Small Cell Lung Carcinoma, Hepatomegaly, Acute Liver Failure, Liver Metastasis


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