Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2023.439
Autopsy and Case Reports
Clinical Case Report

Xanthogranulomatous Endometritis with calculus formation in setting of prolapsed uterus

Nikhil Kumar; Prima Shuchita Lakra; Ranwir Kumar Sinha; Asitava Deb Roy; Debarshi Saha; Jitendra Kumar Sinha

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Abstract

Xanthogranulomatous inflammation is a rare benign inflammatory lesion characterized by sheets of lipid-laden foamy histiocytes. It has been reported in various organs, mainly the kidney and gall bladder. Xanthogranulomatous endometritis (XGE) is sporadic, with only a few cases reported in the English medical literature. Herein, we report a case of xanthogranulomatous endometritis with the formation of stones in a 50-year-old female patient with a prolapsed uterus. Grossly the endometrium was irregular, and the uterine cavity was filled with a yellow friable material, a polypoid growth, and yellowish stones. The microscopy showed sheets of histiocytes with few preserved endometrial glands. In this case, the xanthogranulomatous inflammation may mimic a clear cell carcinoma involving the endometrium and myometrium. One of the important differential diagnoses is malakoplakia. Immunohistochemistry and special stains are helpful in diagnosis.

Keywords

Endometritis, Endometrium, Histiocytes, Uterine Prolapse

References

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Submitted date:
03/31/2023

Accepted date:
06/10/2023

Publication date:
07/19/2023

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