Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2021.396
Autopsy and Case Reports
Autopsy Case Report

Sudden death associated with lipoma of the cerebellopontine angle

Stefano Tambuzzi; Guendalina Gentile; Michele Boracchi; Arnaldo Migliorini

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Abstract

Intracranial lipomas are rare benign tumors considered exceptional when localized in the cerebellopontine angle (CPA), with an incidence of 0.1% of the total number of expansive processes located in this area. We present a case of the sudden death of a 26-year-old young woman in which an unencapsulated neoformation of 0.8 cm was documented at the right cerebellopontine angle and was histologically characterized as intracranial lipoma. The cause of death was then identified as a cardiocirculatory failure secondary to supratentorial (uncal right) herniation caused by the lipoma of the pontocerebellar angle with high-grade diffuse cerebral edema.

Keywords

Brain Neoplasm, Autopsy, Forensic pathology

References

1 Kanaya T, Murai Y, Yui K, Sato S, Morita A. Acoustic neurinoma with synchronous ipsilateral cerebellopontine angle lipoma: A case report and review of the literature. Diagnostics. 2022;12(1):120. http://dx.doi.org/10.3390/diagnostics12010120. PMid:35054286.

2 Totten DJ, Manzoor NF, Perkins EL, Labadie RF, Bennett ML, Haynes DS. Cerebellopontine angle and internal auditory canal lipomas: case series and systematic review. Laryngoscope. 2021;131(9):2081-7. http://dx.doi.org/10.1002/lary.29434. PMid:33567134.

3 Zimmermann M, Kellermann S, Gerlach R, Seifert V. Cerebellopontine angle lipoma: case report and review of the literature. Acta Neurochir. 1999;141(12):1347-51. http://dx.doi.org/10.1007/s007010050440. PMid:10672307.

4 Truwit CL, Barkovich AJ. Pathogenesis of intracranial lipoma: an MR study in 42 patients. AJR Am J Roentgenol. 1990;155(4):855-64. http://dx.doi.org/10.2214/ajr.155.4.2119122. PMid:2119122.

5 Romero-Blanco M, Monteiro-Santos E. Cerebellopontine angle lipoma: a case report. Rev Neurol. 2004;39(3):238-40. PMid:15284964.

6 Brodsky JR, Smith TW, Litofsky S, Lee DJ. Lipoma of the cerebellopontine angle. Am J Otolaryngol. 2006;27(4):271-4. http://dx.doi.org/10.1016/j.amjoto.2005.11.002. PMid:16798407.

7 Hadj Taieb MA, Maamri K, Elkahla G, Darmoul M. A case report of a cerebellopontine angle lipoma revealed by vertigo. Clin Case Rep. 2022;10(3):e05550. http://dx.doi.org/10.1002/ccr3.5550. PMid:35280080.

8 Rodríguez Prado N, Llorente Pendás JL, Gómez Martínez JR, et al. Cerebellopontine angle and internal auditory canal lipomas: report of four cases and review of the literature. Acta Otorrinolaringol Esp. 2004;55(3):126-30. http://dx.doi.org/10.1016/s0001-6519(04)78495-2. PMid:15253339.

9 Debelius A, Rudolph J, Schrom T. Lipoma of the cerebellopontine angle: a case report. Laryngorhinootologie. 2006;85(2):128-31. http://dx.doi.org/10.1055/s-2005-870116. PMid:16498542.

10 Hadj Taieb MA, Maamri K, Elkahla G, Darmoul M. A case report of a Cerebellopontine angle lipoma revealed by vertigo. Clin Case Rep. 2022;10(3):e05550. http://dx.doi.org/10.1002/ccr3.5550. PMid:35280080.

11 Mutlu M, Sagit M, Akin I, Keyik B. An unusual tumour of the cerebellopontine angle. B-ENT. 2009;5(4):269-71. PMid:20163055.

12 Grigoryan GY, Sitnikov AR, Grigoryan YA. Trigeminal nerve lipoma presenting with trigeminal neuralgia: case report and literature review. Zh Vopr Neirokhir Im N N Burdenko. 2021;85(6):102-10. http://dx.doi.org/10.17116/neiro202185061102. PMid:34951767.

13 Bhoi SK, Naik S. Cerebellopontine angle lipoma manifesting as trigeminal neuralgia. J Pediatr. 2020;222:250. http://dx.doi.org/10.1016/j.jpeds.2020.03.037. PMid:32386872.

14 Hung TY, Litofsky NS, Smith TW, Megerian CA. Ganglionic hamartoma of the intracanalicular acoustic nerve causing sensorineural hearing loss. Am J Otol. 1997;18(4):498-500. PMid:9233492.

15 Iplikcioglu C, Bikmaz K, Gokduman CA, Bek S. Cerebellopontine angle lipoma with extracranial extension. J Clin Neurosci. 2006;13(10):1045-7. http://dx.doi.org/10.1016/j.jocn.2006.01.045. PMid:17113988.

16 Scuotto A, Cappabianca S, D’Errico C, et al. Lipomas of the cerebellopontine angle: neuroradiological and surgical considerations. Review of the literature and report of our experience. Clin Neurol Neurosurg. 2013;115(10):2280-3. http://dx.doi.org/10.1016/j.clineuro.2013.07.029. PMid:23962755.

17 Fukui M, Tanaka A, Kitamura K, Okudera T. Lipoma of the cerebellopontine angle: case report. J Neurosurg. 1977;46(4):544-7. http://dx.doi.org/10.3171/jns.1977.46.4.0544. PMid:300430.

18 Fagundes-Pereyra WJ, Marques JA, Carvalho GT, Sousa AA. Lipoma do ângulo pontocerebelar: relato de caso. Arq Neuropsiquiatr. 2000;58(3B):952-7. http://dx.doi.org/10.1590/S0004-282X2000000500028. PMid:11018840.
 


Submitted date:
06/10/2022

Accepted date:
08/13/2022

Publication date:
08/26/2022

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