Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2021.302
Autopsy and Case Reports
Clinical Case Report and Review

Maxillary dentigerous cyst showing squamous odontogenic tumor-like proliferation: surgical approach and literature review

Camila de Oliveira Barbeiro; Roberto Henrique Barbeiro; Heitor Albergoni da Silveira; Luciana Yamamoto de Almeida; Jorge Esquiche León; Andreia Bufalino

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Abstract

  Squamous odontogenic tumor (SOT) is a rare benign neoplasm of the jaw that likely arises from remnants of the dental lamina. It is a slow-growing lesion, with a radiolucent appearance in the central variant. Microscopically, SOT shows islands of squamous epithelium supported by fibrous stroma. In rare cases, squamous odontogenic tumor-like proliferation (SOT-LP) can be observed arising from odontogenic cysts (SOT-LPOC). Herein, we describe the case of a 42-year-old man who presented with discreet bleeding in the maxillary gingiva. Imaging revealed a well-defined, ovoid-shaped lesion with sclerotic margins involving tooth #18 in the intraosseous location. Fine needle aspiration supported the cystic nature of the lesion. After surgery, microscopy revealed a dentigerous cyst showing SOT-LP features. There was no recurrence after a 3-year follow-up. To the best of our knowledge, this is the first report of a dentigerous cyst showing SOT-LP features in the maxilla. Such cysts should be identified to avoid misdiagnosis, with the finding having therapeutic and prognostic implications.

Keywords

Squamous odontogenic tumor, odontogenic cysts, dentigerous cyst, histology

References

1 Pullon PA, Shafer WG, Elzay RP, Kerr DA, Corio RL. Squamous odontogenic tumor. Report of six cases of a previously undescribed lesion. Oral Surg Oral Med Oral Pathol. 1975;40(5):616-30. http://dx.doi.org/10.1016/0030-4220(75)90372-2. PMid:1059063.

2 Elmuradi S, Mair Y, Suresh L, DeSantis J, Neiders M, Aguirre A. Multicentric squamous odontogenic tumor: a case report and review of the literature. Head Neck Pathol. 2017;11(2):168-74. http://dx.doi.org/10.1007/s12105-016-0753-2. PMid:27632187.

3 Chrcanovic BR, Gomez RS. Squamous odontogenic tumor and squamous odontogenic tumor-like proliferations in odontogenic cysts: an updated analysis of 170 cases reported in the literature. J Craniomaxillofac Surg. 2018;46(3):504-10. http://dx.doi.org/10.1016/j.jcms.2017.12.023. PMid:29311021.

4 Parmar RM, Brannon RB, Fowler CB. Squamous odontogenic tumor-like proliferations in radicular cysts: a clinicopathologic study of forty-two cases. J Endod. 2011;37(5):623-6. http://dx.doi.org/10.1016/j.joen.2011.02.010. PMid:21496660.

5 Wright JM Jr. Squamous odontogenic tumorlike proliferations in odontogenic cysts. Oral Surg Oral Med Oral Pathol. 1979;47(4):354-8. http://dx.doi.org/10.1016/0030-4220(79)90259-7. PMid:285403.

6 Leventon GS, Happonen RP, Newland JR. Squamous odontogenic tumor. Am J Surg Pathol. 1981;5(7):671-7. http://dx.doi.org/10.1097/00000478-198110000-00009. PMid:7337159.

7 Fay JT, Banner J, Rothouse L, Kolas S, Klinger BJ, Sayers RJ. Squamous odontogenic tumors arising in odontogenic cysts. J Oral Med. 1981;36(2):35-8. PMid:6942129.

8 Simon JH, Jensen JL. Squamous odontogenic tumor-like proliferations in periapical cysts. J Endod. 1985;11(10):446-8. http://dx.doi.org/10.1016/S0099-2399(85)80084-4. PMid:3865990.

9 Sala-Pérez S, Marco-Molina V, Gay-Escoda C. Squamous odontogenic tumor-like proliferation in a radicular cyst: a case report. J Clin Exp Dent. 2013;5(5):e298-301. http://dx.doi.org/10.4317/jced.51056. PMid:24455099.

10 Laungani N, Hengen S, Nester C, Smith MH. Pericoronal radiolucency surrounding an impacted mandibular molar. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020;129(4):286-9. http://dx.doi.org/10.1016/j.oooo.2019.01.070. PMid:31351918.

11 Unal T, Gomel M, Gunel O. Squamous odontogenic tumor-like islands in a radicular cyst: report of a case. J Oral Maxillofac Surg. 1987;45(4):346-9. http://dx.doi.org/10.1016/0278-2391(87)90358-2. PMid:3470457.

12 Anjana R, Murali N, Malathi N, Suresh RR. Management of a rare case of peripheral squamous odontogenic tumor of the gingiva. J Indian Soc Periodontol. 2016;20(3):336-9. PMid:27563210.

13 Swinson BD, Jerjes W, Thomas GJ. Squamous cell carcinoma arising in a residual odontogenic cyst: case report. J Oral Maxillofac Surg. 2005;63(8):1231-3. http://dx.doi.org/10.1016/j.joms.2005.04.016. PMid:16094597.

14 Oliveira JA, Costa IM, Loyola AM. Squamous odontogenic tumor-like proliferations (SOT-LP) versus intraosseous squamous cell carcinoma in residual cyst. J Oral Maxillofac Surg. 2006;64(8):1325. http://dx.doi.org/10.1016/j.joms.2006.04.026. PMid:16860239.
 


Submitted date:
10/07/2020

Accepted date:
04/13/2021

Publication date:
07/08/2021

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