Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2021.299
Autopsy and Case Reports
Clinical Case Report

Extensive malignant melanoma of the oral cavity: a rare occurrence

Pradeep Pradhan; Amit Kumar Adhya

Downloads: 0
Views: 69

Abstract

Primary malignant melanoma of the oral cavity is a rare tumor in clinical practice. Extensive malignant melanomas are still very rare in the literature. Patients with malignant melanoma of oral cavity are often diagnosed at the advanced stage of the disease due to their painless and nonspecific radiological findings. Histopathology is the gold standard for the final diagnosis and staging of the tumor. Surgery followed by radiotherapy is the standard treatment offered to patients with malignant melanoma. Here we present a rare case of extensive malignant melanoma of oral cavity which was successfully managed by surgical excision followed by adjuvant radiotherapy.

Keywords

Malignant melanoma, Oral cavity, Management

References

1 Sabanathan S, Eng J, Pradhan GN. Primary malignant melanoma of the esophagus. Am J Gastroenterol. 1989;84(12):1475-81. PMid:2688398.

2 Pandey M, Mathew A, Iype EM, Sebastian P, Abraham EK, Nair KM. Primary malignant mucosal melanoma of the head and neck region: pooled analysis of 60 published cases from India and review of literature. Eur J Cancer Prev. 2002;11(1):3-10.

3 Ebenezer J. Malignant melanoma of the oral cavity. Indian J Dent Res. 2006;17(2):94-6. http://dx.doi.org/10.4103/0970-9290.29882. PMid:17051877.

4 Tas F, Keskin S. Mucosal melanoma in the head and neck region: different clinical features and same outcome to cutaneous melanoma. ISRN Dermatol. 2013;2013:586915. http://dx.doi.org/10.1155/2013/586915. PMid:23762595.

5 Strauss JE, Strauss SI. Oral malignant melanoma: a case report and review of literature. J Oral Maxillofac Surg. 1994;52(9):972-6. http://dx.doi.org/10.1016/S0278-2391(10)80083-7. PMid:8064463.

6 Hashemi Pour MS. Malignant melanoma of the oral cavity: a review of literature. Indian J Dent Res. 2008;19(1):47-51. http://dx.doi.org/10.4103/0970-9290.38932. PMid:18245924.

7 Hayashi T, Ito J, Katsura K, et al. Malignant melanoma of the mandibular gingiva; the usefulness of fat saturated MRI. Dentomaxillofac Radiol. 2002;31(2):151-3. http://dx.doi.org/10.1038/sj.dmfr.4600679. PMid:12076058.

8 Smyth AG, Ward-Booth RP, Avery BS, To EW. Malignant melanoma of the oral cavity- an increasing clinical diagnosis? Br J Oral Maxillofac Surg. 1993;31(4):230-5. http://dx.doi.org/10.1016/0266-4356(93)90145-M. PMid:8399039.

9 Clark DB, Priddy RW, Kaburda M. Primary malignant melanoma of the maxillary sinus: case report and literature review. J Oral Maxillofac Surg. 1989;47(7):754-9. http://dx.doi.org/10.1016/S0278-2391(89)80021-7. PMid:2659754.

10 Rapidis AD, Apostolidis C, Vilos G, Valsamis S. Primarymalignant melanoma of the oral mucosa. J Oral Maxillofac Surg. 2003;61(10):1132-9. http://dx.doi.org/10.1016/S0278-2391(03)00670-0. PMid:14586846.

11 Colllins B, LeonBarnes E Jr, Abernethy J. Oral Malignant melanoma. J Clin Oncol. 2005;55:74-108.

12 Femiano F, Lanza A, Buonaiuto C, Gombos F, Di Spirito F, Cirillo N. Oral malignant melanoma: a review of the literature. J Oral Pathol Med. 2008;37(7):383-8. http://dx.doi.org/10.1111/j.1600-0714.2008.00660.x. PMid:18284541.

13 Müller S. Melanin-associated pigmented lesions of the oral mucosa: presentation, differential diagnosis, and treatment. Dermatol Ther. 2010;23(3):220-9. http://dx.doi.org/10.1111/j.1529-8019.2010.01319.x. PMid:20597941.

14 Ebenezer J. Malignant melanoma of the oral cavity. Indian J Dent Res. 2006;17(2):94-6. http://dx.doi.org/10.4103/0970-9290.29882. PMid:17051877.

15 Zitelli JA, Brown CD, Hanusa BH. Surgical margins for excision of primary cutaneous melanoma. J Am Acad Dermatol. 1997;37(3 pt. 1):422-9. http://dx.doi.org/10.1016/S0190-9622(97)70144-0. PMid:9308558.

16 Bouchareb N, Souldi H, Rouadi S, et al. Malignant melanoma of the mandibular gingiva. Rev Laryngol Otol Rhinol (Bord). 2014;135(4-5):207-9. PMid:26521370.

17 Wong JH, Cagle LA, Storm FK, Morton DL. Natural history of surgically treated mucosal melanoma. Am J Surg. 1987;154(1):54-7. http://dx.doi.org/10.1016/0002-9610(87)90289-3. PMid:2440332.

18 Sharma N. Primary oral malignant melanoma: two case reports and review of literature. Case Rep Dent. 2012;2012:975358. http://dx.doi.org/10.1155/2012/975358. PMid:22900212.

19 Sivapathasundharam B. Shafer’s text book of oral pathology. Chennai: Elsevier; 2016. pp. 170-6.

20 Hansson J. Systemic therapy of malignant melanoma. Med Oncol. 1997;14(2):73-81. http://dx.doi.org/10.1007/BF02990951. PMid:9330266.

21 Zitelli JA, Brown CD, Hanusa BH. Surgical margins for excision of primary cutaneous melanoma. J Am Acad Dermatol. 1997;37(3 pt. 1):422-9. http://dx.doi.org/10.1016/S0190-9622(97)70144-0. PMid:9308558.
 


Submitted date:
06/24/2021

Accepted date:
07/18/2021

Publication date:
08/20/2021

611fa3f4a9539558ef3d3cc3 autopsy Articles
Links & Downloads

Autops Case Rep

Share this page
Page Sections