Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2021.258
Autopsy and Case Reports
Clinical Case Report

Congenital medulloblastoma presented in the neonatal period

Patricio García-Espinosa; Max Molina-Ayala; Edgar Botello-Hernández; Estefania Villareal-Garza; Álvaro Barbosa-Quintana

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Abstract

Congenital medulloblastoma is a rare brain tumor that appears in less than 1% of pediatric patients. Congenital medulloblastoma has a poor prognosis and should be suspected in patients with clinical manifestations of hyporeactivity, slow suction reflexes, and the presence of hydrocephalus. Herein we present the case of a 12-day-old female newborn who developed non-communicative hydrocephalus, hyporeactivity, and hyporeflexia. Magnetic resonance imaging of her brain showed a heterogeneous and cystic mass on the posterior cranial fossa. A suboccipital craniotomy was performed. The histopathologic analysis reported a congenital medulloblastoma. She remained in hospital until her death at 112 days old. This is one of the first case reports with clinical-radiological and pathological documentation. Awareness of this diagnosis can allow prenatal intervention, rendering a better prognosis. This case report exemplifies the importance of good prenatal follow-up.

Keywords

Brain Neoplasms, Medulloblastoma, Pathology, Radiology, Case Reports

References

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Submitted date:
11/10/2020

Accepted date:
01/15/2021

Publication date:
04/22/2021

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