Autopsy and Case Reports
Autopsy and Case Reports
Autopsy Case Report

Primary diffuse large B-cell lymphoma of the CNS, with a “Lymphomatosis cerebri” pattern

Balamurugan Thirunavukkarasu; Kirti Gupta; Ritu Shree; Anuj Prabhakar; Aastha Takkar Kapila; Vivek Lal; Bishan Radotra

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We describe an unusual case of lymphomatosis cerebri in a middle-aged lady presenting with rapid-onset dementia. The lymphomatous infiltrate, instead of forming mass lesions, percolated throughout the brain parenchyma, which is often missed on a stereotactic biopsy and hence warrants caution and awareness about this entity. The nonspecific symptoms at presentation and a variable picture at imaging make this entity diagnostically challenging.


Central Nervous System Neoplasm, Lymphomatosis cerebri, Non-Hodgkin lymphoma, Dementia


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