Autopsy and Case Reports
Autopsy and Case Reports
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A rare combination of Dermoid cyst and Cystadenoma: Are collision tumors in the ovary a real entity?

Tushar Kalonia; Neha Kumari; Akanksha Malik; Arvind Kumar; Anupama Bahadur; Sanjeev Kishore

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ABSTRACT: Collision tumors have been reported in various organs like the gastrointestinal tract, lung, skin, adrenals, central nervous system, lymph nodes, uterus, but are rarely seen in the ovary. Collision tumors are two histologically distinct neoplasms in the same organ without any intermixture between them. Here we present a case of a collision tumor of the ovary represented by a mucinous cystadenoma and teratoma. It is imperative for a surgical pathologist to correctly diagnose the collision tumor components and differentiate them from mixed tumors as it will dictate the appropriate treatment based on the individual biological aggressiveness of each component.


Cystadenoma, Mucinous, Ovary, Teratoma


1 Bostanci MS, Yildirim OK, Yildirim G, et al. Collision tumor: dermoid cysts and mucinous cystadenoma in the same ovary and a review of the literature. Obstet Gynecol Cases Rev. 2015;2(2):1-3.

2 Ozbey C, Erdogan G, Pestereli HE, Simsek T, Karaveli S. Serous papillary adenocarcinoma and adult granulosa cell tumor in the same ovary. An unusual case. APMIS. 2005;113(10):713-5. PMid:16309432.

3 Dgani R, Rozenman D, Lifschitz-Mercer B. Granulosa cell tumor arising in an ovary with mature cystic teratoma. Int J Gynaecol Obstet. 1993;41(3):287-9. PMid:8102994.

4 Nirenberg A, Ostor AG, Quinn MA. Collision tumor: serous adenocarcinoma and steroid cell tumor of the ovary. Pathology. 1992;24(2):60-2. PMid:1322520.

5 Kumar V, Abbas A, Fausto N, Aster J. Robbins and Cotran pathologic basis of disease. Philadelphia, Pa: Els Saunders; 2010.

6. Talerman A, Vang R. Germ cell tumor of the ovary. In: Kurman RJ, Ellenson LH, Ronnett BM. Blaustein’s pathology of the female genital tract. 6th ed. Springer; 2011. p. 847-907.

7 Matias-Guiu X, Caixas A, Costa I, Cabezas R, Prat J. Compound medullary-papillary carcinoma of the thyroid: true mixed versus collision tumor. Histopathology. 1994;25(2):183-5. PMid:7982684.

8 Fenoglio CM, Ferenczy A, Richart RM. Mucinous tumors of the ovary. Ultrastructural studies of mucinous cystadenomas with histogenetic considerations. Cancer. 1975;36(5):1709-22.<1709::AID-CNCR2820360526>3.0.CO;2-7. PMid:1192360.

9 Nomura K. Mucin histochemistry of ovarian mucinous cystadenomas expressing gastrointestinal characteristics. Pathol Int. 1995;45(6):430-5. PMid:7581934.

10 Tang P, Soukkary S, Kahn E. Mature cystic teratoma of the ovary associated with complete colonic wall and mucinous cystadenoma. Ann Clin Lab Sci. 2003;33(4):465-70. PMid:14584762.

11 Vang R, Gown AM, Zhao C, et al. Ovarian mucinous tumors associated with mature cystic teratomas. Am J Surg Pathol. 2007;31(6):854-69. PMid:17527072.

12 Brandwein-Gensler M, Urken M, Wang B. Collision tumor of the thyroid: a case report of metastatic liposarcoma plus papillary thyroid carcinoma. Head Neck. 2004;26(7):637-41. PMid:15229907.

13 Fujii K, Yamashita Y, Yamamoto T, et al. Ovarian mucinous tumors arising from mature cystic teratomas: A molecular genetic approach for understanding the cellular origin. Hum Pathol. 2014;45(4):717-24. PMid:24485845.

14 Russel P, Farnsworth A, Russel P, Farnsworth A. Surgical pathology of the ovaries 2nd ed. New York: Churchill Livingstone; 1987. 273-8.

15 Magi-Galluzi C, O’Connell JT, Neffen F. Are mucinous cystadenomas of the ovary derived from germ cells. A genetic analysis. Mod Pathol. 2001;14:140A.

16 Okada S, Ohaki Y, Ogura J, Ishihara M, Kawamura T, Kumazaki T. Computed tomography and magnetic resonance imaging findings in cases of dermoid cyst coexisting with surface epithelial tumors in the same ovary. J Comput Assist Tomogr. 2004;28(2):169-73. PMid:15091118.

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