Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2020.173
Autopsy and Case Reports
Clinical Case Report

Angiomyolipoma of the broad ligament

Satya Dutta; Evarisalin Marbaniang; Biswajit Dey; Bifica Sofia Lyngdoh; Vandana Raphael

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Abstract

Angiomyolipoma is a benign mesenchymal neoplasm of the renal parenchyma, accounting for 1% of all renal parenchymal tumors. However, this entity may rarely occur in extrarenal sites. Extrarenal angiomyolipoma has been documented in various sites of the body, but angiomyolipoma of the broad ligament was reported in only two cases. We report the reputed third case of angiomyolipoma of the broad ligament in a 33-year-old female, who presented clinically with abdominal distension. With a working diagnosis of low-grade neoplasm, an en-bloc excision of the left broad ligament mass was performed. Based on histopathology and immunohistochemistry, a diagnosis of the classical variant of angiomyolipoma of the left broad ligament was made. The post-operative period was uneventful with no recurrence after 6 months of follow-up.

Keywords

Angiomyolipoma, Immunohistochemistry, Adipose Tissue

References

Tsutsumi M, Yamauchi A, Tsukamoto S, Ishikawa S. A case of angiomyolipoma presenting as a huge retroperitoneal mass. Int J Urol. 2001;8(8):470-1. [https://doi.org/10.1046/j.1442-2042.2001.00344.x]. [PMID:11555018]

Minja EJ, Pellerin M, Saviano N, Chamberlain RS. Retroperitoneal extrarenal angiomyolipomas: an evidence-based approach to a rare clinical entity. Case Rep Nephrol. 2012;2012:374107. [https://doi.org/10.1155/2012/374107]. [PMID:24555133]

Eble JN. Angiomyolipoma of kidney. Semin Diagn Pathol. 1998;15(1):21-40. [PMID:9503504]

Goodman ZD, Ishak KG. Angiomyolipomas of the liver. Am J Surg Pathol. 1984;8(10):745-50. [https://doi.org/10.1097/00000478-198410000-00003]. [PMID:6496843]

Katz DA, Thom D, Bogard P, Dermer MS. Angiomyolipoma of the fallopian tube. Am J Obstet Gynecol. 1984;148(3):341-3. [https://doi.org/10.1016/S0002-9378(84)80084-8]. [PMID:6695982]

Laffargue F, Giacalone PL, Charpin C, Lachard A. Uterine angiomyolipoma associated with pregnancy. Gynecol Oncol. 1993;50(3):357-60. [https://doi.org/10.1006/gyno.1993.1225]. [PMID:8406201]

Nelson CP, Sanda MG. Contemporary diagnosis and management of renal angiomyolipoma. J Urol. 2002;168(4 Pt 1):1315-25. [https://doi.org/10.1016/S0022-5347(05)64440-0]. [PMID:12352384]

Liu CH, Chao WT, Lin SC, Lau HY, Wu HH, Wang PH. Malignant perivascular epithelioid cell tumor in the female genital tract: preferred reporting items for systematic reviews and meta-analyses. Medicine. 2019;98(2):e14072. [https://doi.org/10.1097/MD.0000000000014072]. [PMID:30633211]

Mathew M, Nayal B, Rao L, Nagel B. Broad ligament perivascular epithelioid cell tumor (PEComa) of uncertain malignant potential. Turk Patoloji Derg. 2016;32(1):44-6. [PMID:26832182]

Ryś J, Karolewski K, Pudełek J, et al. perivascular epithelioid cell tumor (PEComa) of the falciform/broad ligament. Pol J Pathol. 2008;59(4):211-5. [PMID:19391488]

Kim HJ, Lim SJ, Choi H, Park K. Malignant clear-cell myomelanocytic tumor of broad ligament: a case report. Virchows Arch. 2006;448(6):867-70. [https://doi.org/10.1007/s00428-006-0161-1]. [PMID:16541283]

Fink D, Marsden DE, Edwards L, Camaris C, Hacker NF. Malignant perivascular epithelioid cell tumor (PEComa) arising in the broad ligament. Int J Gynecol Cancer. 2004;14(5):1036-9. [https://doi.org/10.1136/ijgc-00009577-200409000-00045]. [PMID:15361222]

Bonis RT, Domínguez TP, Calatayud FR, Jiménez EC, Piris MA, López-Lucendo NJ. Pelvic PEComa of the broad ligament with lymph node metastases: case report and review of the literature. Arch Esp Urol. 2008;61:744-8. [PMID:18705200]

Chopra R, Al-Mulhim AR, Hashish H. Parametrial angiomyolipoma with multicystic change. Gynecol Oncol. 2003;90(1):220-3. [https://doi.org/10.1016/S0090-8258(03)00251-8]. [PMID:12821370]

Shakuntala PN, Shilpashree M, Geethanjali S, Sharma SK. Acute abdomen as an unusual presentation of broad ligament angiomyolipoma A case report and review of literature. Indian J Surg Oncol. 2012;3(4):276-8. [https://doi.org/10.1007/s13193-012-0169-8]. [PMID:24293961]

Tseng CA, Pan YS, Su YC, Wu DC, Jan CM, Wang WM. Extrarenal retroperitoneal angiomyolipoma: case report and review of the literature. Abdom Imaging. 2004;29(6):721-3. [https://doi.org/10.1007/s00261-004-0179-2]. [PMID:15185030]

Curatolo P, Maria BL. Tuberous sclerosis. Handb Clin Neurol. 2013;111:323-31. [https://doi.org/10.1016/B978-0-444-52891-9.00038-5]. [PMID:23622183]

Dutta S, Dey B, Chanu SM, Raphael V, Khonglah Y. Uterine lipoleiomyoma in peri- and post-menopausal women: a report of three cases. Clin Cancer Investig J. 2019;8:167-70.

Yaegashi H, Moriya T, Soeda S, Yonemoto Y, Nagura H, Sasano H. Uterine angiomyolipoma: case report and review of the literature. Pathol Int. 2001;51(11):896-901. [https://doi.org/10.1046/j.1440-1827.2001.01289.x]. [PMID:11844059]

 

 

 


Publication date:
07/01/2020

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