Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2020.140
Autopsy and Case Reports
Article / Clinical Case Report

Generalized hereditary gingival fibromatosis in a child: clinical, histopathological and therapeutic aspects

John Lennon Silva Cunha; Maria Alice Carvalho da Cruz Ramos; Débora Menezes Regis; Celeste Sanchéz-Romero; Maria Eliane de Andrade; Bruno Torres Bezerra; Ricardo Luiz Cavalcanti de Albuquerque-Júnior

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Abstract

Hereditary gingival fibromatosis (HGF) is a rare genetic condition characterized by slow and progressive gingival enlargement. The gingival overgrowth often delays teeth eruption and may cause serious functional and aesthetic problems. We reported a case of a 10-year-old female child presenting a generalized gingival enlargement covering almost all the maxillary and mandibular teeth and resulted in problems for swallowing, speaking, and poor aesthetics. An incisional biopsy was performed and revealed a hypocellular and hypovascular dense collagenous tissue covered by squamous epithelium exhibiting acanthosis and elongated rete ridges. The diagnosis was HGF. The treatment instituted was an association of gingivectomy with a rigorous program of oral hygiene and follow-up. Herein, we describe a rare non-syndromic case of generalized HGF, including clinical and microscopical features, as well as highlighting the importance of correct diagnosis of this genetic condition.

Keywords

Gingiva, Gingivectomy, Fibromatosis, Gingival, Dentition, Permanent

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Publication date:
01/21/2020

5e26eaad0e8825ee330c3b23 autopsy Articles
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