Autopsy and Case Reports
Autopsy and Case Reports
Article / Clinical Case Report

Peripheral ameloblastoma of the gingiva

Nagaraja Vezhavendhan; Santhanam Vidyalakshmi; Rajakannu Muthukumaran; Arumugam Santhadevy; Muthanandam Sivaramakrishnan; Chandrasekar Gayathri

Downloads: 6
Views: 1668


Peripheral Ameloblastoma (PA) is a benign odontogenic tumor, arising from the cell rest of Serres, reduced enamel epithelium and basal cells of the surface epithelium. Peripheral ameloblastoma is a rare odontogenic neoplasm occurring commonly in the mandibular gingiva. PA clinically resembles other peripherally occurring lesions like pyogenic granuloma, peripheral ossifying fibroma, peripheral giant cell granuloma, and squamous papilloma. The recurrence rate of PA is 16-19% which demands a straight follow up. We report a case of recurrent peripheral ameloblastoma occurring in a 72-year old male located in the mandibular lingual gingiva in relation to the 44, 45 element’s regions. The patient had a primary lesion excised from the same site 6 years before which was diagnosed as ameloblastoma.


Ameloblastoma, Jaw neoplasm, Neoplasm recurrence, local odontogenic tumors


LeCorn DW, Bhattacharyya I, Vertucci FJ. Peripheral ameloblastoma: a case report and review of the literature.

J Endod. 2006;32(2):152-4. []. [PMID:16427467]

Reichart PA, Philipsen HP. Odontogenic tumors and allied lesions. Batavia: Quintessence Publishing Co Inc; 2004. Chapter 6; p. 59-67: Peripheral Ameloblastoma.

Bertossi D, Favero V, Albanese M, et al. Peripheral ameloblastoma of the upper gingiva: report of a case and literature review.

J Clin Exp Dent. 2014;6(2):e180. []. [PMID:24790720]

Martelli-Júnior H, Souza LN, Santos LA, Melo-Filho MR, De Paula AM. Peripheral ameloblastoma: a case report.

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2005;99(5):E31-3. []. [PMID:15829867]

Beena VT, Choudhary K, Heera R, Rajeev R, Sivakumar R, Vidhyadharan K. Peripheral ameloblastoma: a case report and review of literature.

Case Rep Dent. 2012;2012:571509. []. [PMID:22570798]

Zhang X, Tian X, Hu Y, Zhang C, Wei C, Yang X. Oral peripheral ameloblastoma: a retrospective series study of 25 cases.

Med Oral Patol Oral Cir Bucal. 2018;23(3):e277-81. []. [PMID:29680843]

Philipsen HP, Reichart PA, Nikai H, Takata T, Kudo Y. Peripheral ameloblastoma: biological profile based on 160 cases from the literature.

Oral Oncol. 2001;37(1):17-27. []. [PMID:11120479]

Upadhyaya JD, Bhattacharyya I, Fitzpatrick SG, Cohen DM, Islam MN. Peripheral ameloblastoma: a study of 18 cases and usage of Ber-EP4 immunohistochemistry to rule out a diagnosis of intraoral basal cell carcinoma.

J Oral Maxillofac Surg. 2018;76(5):996-1004. []. [PMID:29247621]

Premalatha BR, Patil S, Rao RS, Reddy NP, Indu M. Odontogenic tumor markers - an overview.

J Int Oral Health. 2013;5(2):59-69. [PMID:24155593]

Kaneko T, Nakamura S, Kawano R, Horie N, Shimoyama T. Peripheral ameloblastoma of the mandible: a case report.

J Oral Maxillofac Surg Med Pathol. 2016;28(6):565-8. []. [Internet]

Isomura ET, Okura M, Ishimoto S, Yamada T, Ono Y, Kishino M, Kogo M. Case report of extragingival peripheral ameloblastoma in buccal mucosa.

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2009;108(4):577-9. []. [PMID:19778743]

On DH, Kang MH, Ryu J, Kang M. Peripheral ameloblastoma of the pterygomandibular space: a case report.

J Oral Maxillofac Surg Med Pathol. 2019;31(3):192-5. [].

Baden E, Doyle JL, Petriella V. Malignant transformation of peripheral ameloblastoma.

Oral Surg Oral Med Oral Pathol. 1993;75(2):214-9. []. [PMID:8426721]

Hunter KD, Speight PM. The diagnostic usefulness of immunohistochemistry for odontogenic lesions.

Head Neck Pathol. 2014;8(4):392-9. []. [PMID:25409846]

Brown NA, Betz BL. Ameloblastoma: a Review of Recent Molecular Pathogenetic Discoveries.

Biomark Cancer. 2015;7(Suppl 2):19-24. []. [PMID:26483612]






















Publication date:

5df3e45d0e8825357473a14b autopsy Articles
Links & Downloads

Autops Case Rep

Share this page
Page Sections