Autopsy and Case Reports
Autopsy and Case Reports
Article / Clinical Case Report

Solitary pancreatic renal cell carcinoma metastasis

Miguel Nogueira; Sílvia Costa Dias; Ana Catarina Silva; João Pinto; Jorge Machado

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Pancreatic metastases are rare; they account for only 2% of all pancreatic malignancies and usually occur when associated with a disseminated metastatic disease. Solitary pancreatic metastases are even less frequent, and there are few reports regarding surgical resection. We report the case of a 77-year-old female patient diagnosed with a single cephalo-pancreatic metastasis of renal cell carcinoma, 16 years after a total nephrectomy. The patient underwent successful pancreaticoduodenectomy, and the diagnosis was confirmed. A subsequent positron emission tomography (PET) scan showed disease relapse, and tyrosine kinase inhibitor treatment with sunitinib was initiated. After 1 year and 4 months, the PET-computed tomography scan showed a complete radiologic response.


Neoplasm Metastasis, Carcinoma, Kidney Neoplasm, Pancreas


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