Autopsy and Case Reports
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A second reported malignancy in a patient with Morquio syndrome

Ameer Hamza; Sidrah Khawar; Ahmad Ibrahim; Jacob Edens; Crystal Lalonde; Robert D. Danforth

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Morquio syndrome is a rare lysosomal storage disease that affects multiple organ systems. However, it is rarely associated with malignancy. We present the case of a 30-year old man with Morquio syndrome associated with gastric adenocarcinoma. This case also demonstrates two other findings that have not been previously described in patients with Morquio syndrome - malrotation of brainstem and cerebellum, without clinical neurologic deficit, and persistence of fetal lobulation in the kidneys.


Lysosomal storage diseases; Mucopolysaccharidosis IV; Stomach Neoplasm


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