Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2017.010
Autopsy and Case Reports
Article / Autopsy Case Report

Disseminated invasive aspergillosis in a prolonged stay in the intensive care unit

Gajender Singh, Sonu Kalyan, Sant Prakash Kataria, Jyoti Sharma, Padam Parmar, Meenu Gilotra, Rajeev Sen

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Abstract

Aspergillus is a common cause of invasive mycosis, especially in immunocompromised individuals. We report the case of a 62-year-old male who was hospitalized after suffering severe physical injuries and died after few weeks of hospitalization. A medicolegal autopsy was conducted, and various organs were sent for histopathological examination of which heart, lungs, and kidneys showed extensive involvement by aspergillus. Thus, a diagnosis of disseminated invasive aspergillosis was made on autopsy, which itself is a rare entity. This case report illustrates a prolonged stay in the intensive care unit as a possible risk factor for the development of disseminated aspergillosis.

Keywords

Aspergillosis; Intensive Care Units; Multiple Trauma; Respiration, Artificial; Autopsy.

References

1. Aleksenko A, Gyasi RK, Gyasi RK. Disseminated invasive aspergillosis. Ghana Med J. 2006;40(2):69-72. PMid:17299570. http://dx.doi.org/10.4314/gmj.v40i2.36021.

2. Cishek MB, Yost B, Schaefer S. Cardiac aspergillosis presenting as myocardial infarction. Clin Cardiol. 1996;19(10):824-7. PMid:8896916. http://dx.doi.org/10.1002/clc.4960191012.

3. Vaideeswar P, Prasad S, Deshpande JR, Pandit SP. Invasive pulmonary aspergillosis: a study of 39 cases at autopsy. J Postgrad Med. 2004;50(1):21-6. PMid:15047994.

4. Feng D, Heffner R, Wright J. Invasive aspergillosis extensively involving the brain and multiple organs in a bone marrow transplant patient. The Internet Journal of Pathology. 2007;7:1-7.


Publication date:
03/31/2017

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