Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2016.040
Autopsy and Case Reports
Image in Focus

Periprostatic venous thrombosis

Eduardo Paulino Júnior, Pedro Lobo Alcântara Neves, Luiz Otávio Savassi Rocha

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Abstract

Figure. Pathological findings of a 33-year-old male who underwent a craniotomy for resection of a WHO grade 2 frontal lobe oligodendroglioma; A - Coronal section of the encephalic frontal lobe showing a poorly defined reddish smooth mass in the cortex and white matter, with enlargement of the affected area, especially the superior frontal gyrus on the left hemisphere; B - Photomicrography of the central nervous system tumor depicting a diffusely infiltrating glioma composed of monomorphic cells with uniform round vesicular nuclei, distinct small nucleoli, and perinuclear halo (“fried egg appearance”); C - Gross examination of the prostate gland and surrounding tissue with extensive recent periprostatic venous thromboses; D - Gross examination of the lung showing a wedge-shaped, hemorrhagic area, based on the pleura, which corresponds to a recent pulmonary infarct due to a pulmonary embolism.

Keywords

Cancer, Glioma, Neurosurgery, Pulmonary embolism, Periprostatic venous thrombosis

References

1. Wesseling P, van den Bent M, Perry A. Oligodendroglioma: pathology, molecular mechanisms and markers. Acta Neuropathol. 2015;129(6):809-27. http://dx.doi.org/10.1007/s00401-015-1424-1. PMid: 25943885.

2. Smith TR, Nanney AD 3rd, Lall RR, et al. Development of venous thromboembolism (VTE) in patients undergoing surgery for brain tumors: results from a single center over a 10 year period. J Clin Neurosci. 2015;22(3):519-25. http://dx.doi.org/10.1016/j.jocn.2014.10.003. PMid:25533212.

3. Simanek R, Vormittag R, Hassler M, et al. Venous thromboembolism and survival in patients with high-grade glioma. Neuro-oncol. 2007;9(2):89-95. http://dx.doi.org/10.1215/15228517-2006-035. PMid:17327573.

4. Magnus N, Garnier D, Meehan B, et al. Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations. Proc Natl Acad Sci USA. 2014;111(9):3544-9. http://dx.doi.org/10.1073/pnas.1314118111. PMid:24520174.

5. Hamada K, Kuratsu J, Saitoh Y, Takeshima H, Nishi T, Ushio Y. Expression of tissue factor correlates with grade of malignancy in human glioma. Cancer. 1996;77(9):1877-83. http://dx.doi.org/10.1002/(SICI)1097-0142(19960501)77:9<1877::AIDCNCR18>3.0.CO;2-X. PMid:8646688.

6. Jo JT, Schiff D, Perry JR. Thrombosis in brain tumors. Semin Thromb Hemost. 2014;40(3):325-31. http://dx.doi.org/10.1055/s-0034-1370791. PMid: 24599439.

7. D’Asti E, Fang Y, Rak J. Brain neoplasms and coagulationlessons from heterogeneity. Rambam Maimonides Med J. 2014;5(4):e0030. http://dx.doi.org/10.5041/RMMJ.10164. PMid: 25386346.

8. Reddy PV, Solomon D. Pulmonary emboli from massive thrombosis of the periprostatic venous plexus mimicking acute respiratory distress syndrome. Chest. 2003;124(4):251S. http://dx.doi.org/10.1378/chest.124.4_MeetingAbstracts.251S.

9. Elhammady G, Schubeck AT, El-Najjar V, Robinson MJ. Postmortem demonstration of the source of pulmonary thromboembolism: the importance of the autopsy. Case Rep Vasc Med. 2011(2011):1-3. http://dx.doi.org/10.1155/2011/108215. PMid: 22937459.

10. Nathoo N, Caris EC, Wiener JA, Mendel E. History of the vertebral venous plexus and the significant contributions of Breschet and Batson. Neurosurgery. 2011;69(5):1007-14, discussion 1014. PMid:21654535.


Publication date:
09/29/2016

57ed4ae80e88257c49dbebfd autopsy Articles
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