Autopsy and Case Reports
https://autopsyandcasereports.org/article/doi/10.4322/acr.2012.022
Autopsy and Case Reports
Article / Autopsy Case Report

Pheochromocytoma-induced shock: a case report

Stanley de Almeida Araújo; Paula Alves Santos do Carmo; Eduardo Paulino Júnior; Isabela Nascimento Borges; Luiz Otávio Savassi Rocha

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Abstract

Because of its rarity, together with the variability and nonspecificity of its signs and symptoms, pheochromocytoma, a tumor arising from chromaffin cells, creates an unlucky paradox: it is often missed but only rarely found. Besides the association with arterial hypertension, often in the form of paroxysmal attacks, pheochromocytoma may also be associated, in up to 40% of cases, with orthostatic hypotension which, when present, provides a clue to the diagnosis of the tumor. Far more rare (about 2% of cases) is the clinical presentation in the form of shock, a possibility that, among other attributes, justifies the epithet “the great mimic” applied to the neoplasia. The authors report the case of a 51-year-old hypertensive woman whose death was erroneously attributed to septic shock. Autopsy disclosed an unsuspected left adrenal bulky pheochromocytoma with areas of hemorrhage and extensive central necrosis, pronounced pulmonary edema, left ventricular mural thrombus, and histological evidence of acute myocardial injury.

Keywords

Pheochromocytoma, Shock, Autopsy.

Publication date:
01/13/2016

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